THE EFFECTS OF BAY K-8644 ON AGONIST-INDUCED CONTRACTIONS IN GUINEA-PIG URINARY-BLADDER
ACTA PHARMACEUTICA JUGOSLAVICA, vol.41, no.3, pp.211-216, 1991 (SCI-Expanded)
- Publication Type: Article / Article
- Volume: 41 Issue: 3
- Publication Date: 1991
- Journal Name: ACTA PHARMACEUTICA JUGOSLAVICA
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
- Page Numbers: pp.211-216
- Dokuz Eylül University Affiliated: No
Abstract
In this study the effects of Bay K 8644 a new Ca2+ channel activator, on agonist-induced contractions in guinea-pig urinary bladders were investigated. Histamine and serotonin (10(-9) - 10(-4) M) produced a dose-dependent contraction. Maximum contraction was obtained by 10(-5) M serotonin. Its value was 990.00 mg.