The Metabolic Impacts of Nitric Oxide and its metabolites: A Brief Review


Tatlıbal P., Oral O., Nomikos G. N., Nomikos N. N.

Biomed J Sci & Tech Res, cilt.43, sa.3, ss.34524-34526, 2022 (Hakemli Dergi)

Özet

Background: The study aims to investigate and evaluate the metabolic impacts of nitric oxide on body functions for a healthy living. Materials and Methods: In the search for scientific literatures related to this review the US National Library of Medicine (PubMed), MEDLINE and Sport Discus data and the terms “endothelium-derived relaxing factor (EDRF)”, “nitric oxide”, ‘’nitric oxide metabolites’’ and ‘’health ‘’were used. Results: While almost all known free oxygen radicals are harmful at any concentration, nitric oxide (NO) plays a role in the regulation of many important physiological events such as blood pressure, sportive performance and immunological functions at low concentrations. Conclusion: Nitrite Oxide (NO) is located in the guanidine group of the arginine amino acid, formed as a result of the reaction of nitrogen atom and molecular oxygen, and is a lipid and water-soluble free radical with many metabolic functions and also some pathophysiological mechanisms.