Tuberculosis risk in the biologic era: tuberculin skin test conversion rates in children with rheumatologic diseases


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ÖZLÜ C., TÜRKUÇAR S., KARAOĞLU ASRAK H., ADIGÜZEL DUNDAR H., ÜNSAL Ş. E., BELET N.

TURKISH JOURNAL OF PEDIATRICS, cilt.63, sa.6, ss.978-985, 2021 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 63 Sayı: 6
  • Basım Tarihi: 2021
  • Doi Numarası: 10.24953/turkjped.2021.06.005
  • Dergi Adı: TURKISH JOURNAL OF PEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.978-985
  • Anahtar Kelimeler: biological agents, tuberculosis, children, TNF-alpha inhibitors, tocilizumab, canakinumab, LATENT TUBERCULOSIS, SCREENING-TESTS, INFECTION
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background. The widespread use of biological treatments has increased the frequency of opportunistic infections such as tuberculosis (TB). The primary objective of our study was to determine the rate of tuberculin skin test (TST) conversion during biological therapy. The secondary objective was to monitor the side effects related to isoniazid (INH) prophylaxis, in the selected subgroup.