Risk factors, locations of the thrombus, prophylaxis, and treatment of the deep venous thrombosis patients in the İzmir City and Aegean Region: Results of a multicenter study

Karaçelik M., Kara E., Erdinç I., Özelçi A. B., Atalay C. S., OĞUZ E., ...More

Turkiye Klinikleri Cardiovascular Sciences, vol.23, no.2, pp.115-120, 2011 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 2
  • Publication Date: 2011
  • Journal Name: Turkiye Klinikleri Cardiovascular Sciences
  • Journal Indexes: Scopus
  • Page Numbers: pp.115-120
  • Keywords: Risk factors, Venous thrombosis
  • Dokuz Eylül University Affiliated: Yes


Objective: To determine whether there is a relationship between the risk factors and the locations of the thrombi, pharmacological prophylaxis, and the treatment modalities in patients with deep venous thrombosis (DVT) in the İzmir City and Aegean Region. Material and Method: We enrolled 531 consecutive patients with DVT which are confirmed by Doppler ultrasound and reviewed records of 13 hospitals in the Izmir City and Aegean Region, in this multicenteric cross-sectional study. The data of the patients were recorded on a questionnaire form and analyzed by using confidence intervals for odds ratios, Chi-square test and Student-t tests. Results: 85.3% of the patients were outpatients while 14.7% were inpatients. The most frequently encountered medical risk factors were chronic venous insufficiency-varices, immobilization and family history respectively. The most frequently seen surgical risk factors were lung cancer surgery and knee surgery, followed by gastrointestinal surgery in the surgical group. While DVT were seen more frequent in males who had lung cancer, chronic obstructive pulmonary disease and under chemotherapy receiving patients for a malignancy; otherwise, DVT was seen more frequently in females who were obese and had a hip fracture. Conclusion: Advanced age is a crucially important risk factor in population for DVT and be able to treat with low molecular weight heparin without hospitalization as outpatient settings especially, for pregnant or mothers in lactation period. Malignity and its related surgery are at the forefronts of DVT causes. The obese females are in danger for DVT if any surgery is planned. The population-based studies are needed to be planned to detect for the true prophylaxis rates. Copyright © 2011 by Türkiye Klinikleri.