Synthesis of Cycloalk[b]indole Bearing Spiropiperidine Derivatives

GÜNDOĞDU HIZLIATEŞ C., Gulle S., Ergun Y.

JOURNAL OF HETEROCYCLIC CHEMISTRY, cilt.53, sa.1, ss.249-254, 2016 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 53 Sayı: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1002/jhet.2395
  • Dergi Adı: JOURNAL OF HETEROCYCLIC CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.249-254
  • Anahtar Kelimeler: Tetrahydrocarbazolones, sedative and hypnotic drugs, indole containing compounds, piperidinedione, AMINOGLUTETHIMIDE, OXIDATION, ALKALOIDS
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

The novel heterocyclic compounds that have cycloalk[b]indole moiety bearing spiropiperidinone and spiropiperidinedione (3a, 3b, 3c, 5a, 5b, 8a, 8b, and 10a) were synthesized for the first time. The synthesis of spiropiperidinone and spiropiperidinedione structures was performed by a new method. These compounds are similar to sedative and hypnotic drugs such as methyprylon, glutethimide, and thalidomide.