Clinical quiz: A pediatric case presenting with fever and diffuse myalgia
RHEUMATOLOGY INTERNATIONAL, vol.25, no.4, pp.314-316, 2005 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 25 Issue: 4
- Publication Date: 2005
- Doi Number: 10.1007/s00296-004-0530-5
- Journal Name: RHEUMATOLOGY INTERNATIONAL
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.314-316
- Keywords: familial Mediterranean fever, myalgia, protracted febrile myalgia syndrome
- Dokuz Eylül University Affiliated: Yes
Abstract
Familial Mediterranean fever (FMF) is a multisystem disease characterized by recurrent polyserositis episodes seen in certain ethnic groups. In recent years the clinical picture of FMF has been expanded and severe myalgia is a frequently recognized component of the syndrome. Protracted febrile myalgia syndrome (PFMS), characterized by severe paralyzing myalgia, high fever, abdominal pain, diarrhea, arthritis/arthralgia, and transient vasculitic rashes mimicking Henoch-Schonlein purpura, was first described in patients with FMF in 1994. We describe an 11-year-old Turkish girl with a second attack of PFMS before being diagnosed as having FMF, emphasizing the importance of myalgia for the diagnosis of FMF even in the absence of other symptoms.