Carnitine Protects the Intestine Against Reperfusion Injury in Rats

HOŞGÖRLER F. U., ATİLA K., Terzi C., Akhisaroglu S. T., OKTAY G., Kupelioglu A., ...Daha Fazla

JOURNAL OF SURGICAL RESEARCH, cilt.159, sa.1, ss.603-610, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 159 Sayı: 1
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1016/j.jss.2009.03.028
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.603-610
  • Anahtar Kelimeler: intestinal ischemia, reperfusion injury, carnitine, intestinal anastomosis, L-PROPIONYL-CARNITINE, ISCHEMIA-REPERFUSION, MESENTERIC ISCHEMIA, MUCOSAL INJURY, ALLOPURINOL, REAPPRAISAL, ANASTOMOSIS, METABOLISM, NEUTROPHIL, OXYGEN
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background. Although the negative effects of ischemia on anastomotic healing have been shown in many studies, there is no adequate information on the effects of reperfusion injury. Therefore, in this study, we investigated the effect of ischemia-reperfusion (ER) injury on intestinal anastomosis and the protective efficiency of carnitine in an experimental relatively short intestinal ischemia and long duration reperfusion model.