Comparison of analgesic effects of intraarticular clonidine and morphine-bupivacaine combination following knee artroscopy Diz artroskopisi sonrasi intraartikuler uygulanan klonidin ile morfin/bupivakain kombinasyonun analjezik etkinliginin karsilastirilmasi


GÖKMEN A. N., KÜÇÜKGÜÇLÜ S., Iyilikci L., ARKAN A., TAPLU A., Erdem O., ...Daha Fazla

Turk Anesteziyoloji ve Reanimasyon, cilt.27, sa.5, ss.233-237, 1999 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 5
  • Basım Tarihi: 1999
  • Dergi Adı: Turk Anesteziyoloji ve Reanimasyon
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.233-237
  • Anahtar Kelimeler: Arthroscopy, Intraarticular clonidine, Postoperative analgesia
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

In this study, 39 patients who underwent elective artroscopic knee surgery were divided into three groups in a randomized pattern according to the selected postoperative analgesic treatment. All patients received the same anaesthetic protocol. In morphine and bupivacaine group (Group MB), 2 mg morphine and 20 mL % 5 bupivacaine was (100mg); in clonidine group (Group K), 150 μg clonidine in 20 mL serum physiologic; in serum physiologic group (Group SF) only 20 mL serum physiologic were administered with intraarticular injection for postoperative analgesia. A visual analogue scala (VAS) was used for the pain assessment at 1/2, 1, 2, 3, 6, 12 and 24 hours postoperatively. Mean arterial pressure, heart rate and side effects of treatment protocols were also, compared between groups. The duration of postoperative analgesia was as follows; 765.24±125.6 min for group K, 134.08±16.4 min for group MB, 64.04±11.3 min for group SF (p<0.05). When the VAS scores of group MB and K were compared there was no statistically significant difference at postoperative 1/2, 1, 2 and 24 h.; however, at postoperative 3, 6 and 12 h the difference was statistically significant (p<0.05). When the VAS scores of MB and K groups were compared with that of SF group, there was statistically significant difference at all hours. We observed urinary retention following intraarticular morphine administration only in one patient. We didn't observe side effects due to intraarticular clonidine administration. As a result, we concluded that 150 μg intraarticular clonidine administration during arthroscopic knee surgery is an effective and practical method for postoperative pain treatment.