FACTORS INFLUENCING PROLONGED HOSPITALIZATION IN SKIN AND SOFT TISSUE INFECTIONS: A SINGLE-CENTRE RETROSPECTIVE COHORT STUDY DERİ VE YUMUŞAK DOKU ENFEKSİYONLARINDA HASTANE YATIŞ SÜRESİNİ ETKİLEYEN FAKTÖRLER: TEK MERKEZLİ RETROSPEKTİF KOHORT ÇALIŞMA

Çaşkurlu H., Sarı M., Ocak S. G., Akbal H. V., EMECEN A. N., Savurmuş K., ...Daha Fazla

Nobel Medicus, cilt.22, ss.35-45, 2026 (ESCI, Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22
  • Basım Tarihi: 2026
  • Dergi Adı: Nobel Medicus
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, EMBASE, Academic Search Ultimate (EBSCO), Biomedical Reference Collection: Corporate Edition (EBSCO)
  • Sayfa Sayıları: ss.35-45
  • Anahtar Kelimeler: duration of therapy, length of stay, risk factors, risk faktörleri, Soft tissue infections, tedavi süresi, yatış süresi, Yumuşak doku enfeksiyonları
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: This study aimed to characterize the clinical, laboratory, radiological, and treatment features of patients hospitalized with skin and soft tissue infections (SSTIs) and to evaluate factors associated with prolonged hospitalization. Material and Method: This retrospective single-center cohort study was conducted on 105 patients who followed up for Skin Soft Tissue Infections (SSTIs) at Prof. Dr. Süleyman Yalçın Göztepe City Hospital between 2021 and 2022. Demographic, clinical, laboratory, imaging, and treatment data were collected. Patients were grouped by hospital stay length: <14 days and ≥14 days. Group comparison was made using chi-square and Student’s t-test or Mann–Whitney U test. Univariable and multivariable logistic regression analyses were conducted. Results: The mean age was 61.3±16.2 years old (48.6% female). Comorbidities were present in 87.6%, especially diabetes (50.5%) and hypertension (40%). SSTIs mainly affected the lower extremities (71.4%). Erythema (87.6%), fever (43.8%), and warmth (42.9%) were the most common symptoms. Cellulitis (66.7%) and diabetic foot infections (22.9%) were the main diagnoses. Prior antibiotic use was reported in 62.9%. Tissue cultures were positive in 72.2% of the 54 cases, frequently identifying Enterococcus faecalis and Staphylococcus aureus. Empirical treatments included piperacillin-tazobactam and clindamycin; 38.1% required antibiotic changes. Median hospital stay was 8 days; 24.8% stayed ≥14 days. Longer stays were significantly associated with diabetes (39.6% vs. 9.6%, p=0.001), abnormal Doppler ultrasound (38.7% vs. 10.0%, p=0.01), and need for surgery (85.7% vs. 20.4%, p=0.001). CRP values were significantly higher in patients hospitalized for long periods. Culture positivity and pathogen type did not affect length of stay. Conclusion: Identifying high-risk patients early, using imaging and culture-guided therapy, and timely surgical intervention can help reduce hospital stays and improve outcomes in SSTI cases.