Retrospective investigation of Interleukin IL-1 and IL-6 genes polymorphism among elderly patients with sarcopenia in the Turkish population

Tasar P. T.

GENETICS AND MOLECULAR RESEARCH, vol.17, no.1, 2018 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 1
  • Publication Date: 2018
  • Doi Number: 10.4238/gmr16039881
  • Journal Name: GENETICS AND MOLECULAR RESEARCH
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Keywords: Sarcopenia, Old age, Interleukin 1 and 6 genes, MUSCLE STRENGTH, OLDER-PEOPLE, TNF-ALPHA, ASSOCIATION, PROFILES, HEALTH, MODEL, RISK, MEN
  • Dokuz Eylül University Affiliated: Yes

Abstract

Introduction: Sarcopenia, one of the geriatric syndromes, is defined as generalized and progressive reduction in skeletal muscle mass accompanied by loss of muscle strength and/or function. There is a paucity of research in the Turkish population about the effects of interleukin 1 (IL-1) and IL-6 gene polymorphism on sarcopenia. The aim of this study was to evaluate the relationship between IL-1 and IL-6 gene polymorphism and sarcopenia in the older Turkish population.