STROMAL-PREDOMINANT MESENCHYMAL HAMARTOMA OF THE LIVER WITH ELEVATED SERUM ALPHA-FETOPROTEIN LEVEL


Gunes D., Uysal K. M., Cecen E., Cakmakci H., ÖZER E., Akgur F. M., ...More

PEDIATRIC HEMATOLOGY AND ONCOLOGY, vol.25, no.7, pp.685-692, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 7
  • Publication Date: 2008
  • Doi Number: 10.1080/08880010802313731
  • Journal Name: PEDIATRIC HEMATOLOGY AND ONCOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.685-692
  • Keywords: elevated AFP, infant liver tumors, mesenchymal hamartoma, stromal predominant pattern, FLOW-CYTOMETRIC ANALYSIS, EMBRYONAL SARCOMA, FEATURES, TRANSLOCATION, CHILDREN, CANCER
  • Dokuz Eylül University Affiliated: Yes

Abstract

Mesenchymal hamartoma of the liver (MHL) is an uncommon, benign, tumor-like lesion and is usually diagnosed in the first 2 years of life. Its pathogenesis remains unclear. Treatment of choice is radical excision. The authors report a case of solid stromal predominant MHL in a 12-month-old male infant who also had an elevated serum alpha-fetoprotein level. He also had hypospadias, which might represent a spectrum of developmental anomalies. It usually presents as an asymptomatic mass, however, as in the reported case, it may cause several complications due to the compression of surrounding structures. He was successfully treated with total excision of the pedunculated large tumor without any complication.