Akademik Veri Yönetim Sistemi
Turk Anesteziyoloji ve Reanimasyon, cilt.30, sa.6, ss.173-180, 2002 (Scopus)
We aimed to study the effects of rocuronium and succinylcholine on the quality of rapid sequence intubation, hemodynamic effects on the mother and neurologic and physiologic effects on the fetus. Eighty term pregnant patients were randomly divided into 4 groups each containing 20. For the induction of anesthesia, patients received 0.6 mg/kg rocuronium following 2 mg/kg propofol in rocuronium-propofol (R-P) group, 0.6 mg/kg rocuronium following 5 mg/kg thiopentone in rocuronium-thiopentone (R-T) group, 1.5 mg/kg succinylcholine following 2 mg/kg propfol in succinylcholine-propofol (S-P) group and 1.5 mg/kg succinylcholine following 5. mg/kg thiopentone in succinylcholine-thiopentone (S-T) group. Twenty seconds after injection of neuromuscular blocking agent preparation for laryngoscopy was started and patients were intubated according to clinical conditions. Neuromuscular conduction was evaluated with the motor response in musculus adductor pollicis by using stimulations in the form of TOF with TOF-Guard nerve stimulator. After the delivery of the fetus umbilical arterial/venous pH, PaO2, PaCO2, HCO3, SaO2 values were measured, 1. and 5. min APGAR scores were recorded. Mean time to intubation was between 38-42 seconds when appropriate clinical conditions were reached and there was no diffrence in quality of intubation between groups. When the mean onset of actions for each group were compared, there was a significant difference between the group R-P (90.00±23.30 sec) and groups S-P (48.42±18.64 sec) and S-T (57.50±16.53 sec) (p<0.05) and between the group R-T (107.33±40.08 sec) and groups S-P (48.42±18.64 sec) and S-T (57.50±16.53 sec) (p<0.05). We concluded that rocuronium can be used for rapid intubation during cesarian section if succinylcholine is contraindicated.