Effects of Early Litter Loss on Maternal Behavior and Subsequent Generations in Rats: An Attempt for an Animal Model for Loss of a Baby

Ozbek A., Akhisaroglu M., Dursun O. B., Tas F. V., YILMAZ O., Semin I.

NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, vol.48, no.1, pp.44-52, 2011 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 1
  • Publication Date: 2011
  • Doi Number: 10.4274/npa.y5700
  • Journal Name: NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.44-52
  • Keywords: Complicated grief, litter loss, maternal behavior, blood corticosterone level, learning, PRENATAL STRESS, OFFSPRING RATS, ADULT RATS, ANXIETY, CARE, ENVIRONMENT, SEPARATION, MEMORY, MECHANISMS, EXPRESSION
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objective: Loss of a baby accompanied by complicated grief increases vulnerability to mental disease with adverse consequences both for the mother and the long-term well-being of the subsequent generations. This study presents an animal model and aims to study the reactions of female rats to the loss of their litters and the consequences for the next litter.