Evaluation of Lamivudine Resistance Assay Using a Molecular Method in Patients with Chronic Hepatitis B


Kose Ş., Turken M., Gul S.

VIRAL HEPATIT DERGISI-VIRAL HEPATITIS JOURNAL, vol.21, no.1, pp.17-19, 2015 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 1
  • Publication Date: 2015
  • Doi Number: 10.4274/vhd.42204
  • Journal Name: VIRAL HEPATIT DERGISI-VIRAL HEPATITIS JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.17-19
  • Keywords: Lamivudine, resistance, chronic hepatitis B
  • Dokuz Eylül University Affiliated: No

Abstract

Objective: Lamivudine is a nucleoside analogue approved by the FDA in 1998 for the treatment of chronic hepatitis B. Its unique disadvantage compared to other antiviral agents used in hepatitis B treatment is the emergence of drug resistance during treatment. In this study, we aimed to determine lamivudine resistant mutations.