Evaluation of Lamivudine Resistance Assay Using a Molecular Method in Patients with Chronic Hepatitis B

Kose Ş., Turken M., Gul S.

VIRAL HEPATIT DERGISI-VIRAL HEPATITIS JOURNAL, cilt.21, sa.1, ss.17-19, 2015 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 1
  • Basım Tarihi: 2015
  • Doi Numarası: 10.4274/vhd.42204
  • Dergi Adı: VIRAL HEPATIT DERGISI-VIRAL HEPATITIS JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.17-19
  • Anahtar Kelimeler: Lamivudine, resistance, chronic hepatitis B
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Objective: Lamivudine is a nucleoside analogue approved by the FDA in 1998 for the treatment of chronic hepatitis B. Its unique disadvantage compared to other antiviral agents used in hepatitis B treatment is the emergence of drug resistance during treatment. In this study, we aimed to determine lamivudine resistant mutations.