Research Information System
JOURNAL OF UROLOGY, vol.147, no.1, pp.42-46, 1992 (SCI-Expanded, Scopus)
Arterial and venous systems are the main points for the evaluation of vasculogenic impotence. To evaluate both of these systems in the same study we propose a dual radioisotopic study in which technetium-99m (Tc-99m) and xenon-133 (Xe-133) were used. The changes in Tc-99m and Xe-133 radioactivities administered intravenously and intracavernously, respectively, were monitored before and after intracavernous papaverine injection. These changes were determined as time activity curves, which were generated from the region of interest over the penis. A Tc-99m penogram index derived from the Tc-99m time activity curve was significantly different in the control and arteriogenic impotence groups (131.67 +/- 74.6 versus 62.94 +/- 51.6, p < 0.01). A meaningful correlation between Tc-99m penogram index results and duplex ultrasonographic findings were observed (r = 0.905). Xe-133 penogram index, derived from the Xe-133 washout curve was significantly different in the control and venogenic impotence groups (-25.65 +/- 24.9 versus -56.09 +/- 13.4, p < 0.01). Also, a meaningful correlation was obtained between pharmacocavernosometry and Xe-133 penogram index results of venogenic impotent patients (r = 0.86). These findings suggest that the dual radioisotopic study will be a useful technique in the evaluation of the entire vascular system of the penis, since it is a noninvasive method.