Prognostic Factors and Scoring Systems in Chronic Myelomonocytic Leukemia: A Retrospective Analysis of 37 Patients

DEMİRKAN F., ALACACIOĞLU İ., Piskin O., ÖZSAN G. H., ÖZCAN M., ÜNDAR B.

UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI, cilt.18, sa.4, ss.193-200, 2008 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 4
  • Basım Tarihi: 2008
  • Dergi Adı: UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.193-200
  • Anahtar Kelimeler: Chronic myelomonocytic leukemia, Myelodysplastic syndrome, Scoring systems, Prognostic factors, HEALTH-ORGANIZATION CLASSIFICATION, PRIMARY MYELODYSPLASTIC SYNDROMES, SINGLE INSTITUTION, PROPOSALS, CMML, SURVIVAL
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Main objective of this study was to evaluate hematological, clinical and demographic features of our chronic myelomonocytic leukemia (CMML) patients according to different classification systems and prognostic variables. Thirty-seven consecutive patients with CMML diagnosed between February 1994 and December 2005 were evaluated retrospectively. Male and female ratio was 29/8. The median age at diagnosis was 72. Median follow-up time for all patients was 12 months (1-119 months). 70.3% of patients were classified as CMML-MP, others were classified as CMML-MD type according to FAB. When they were reclassified according to WHO, 86.5% of them were CMML-I and 13.5% were CMML-II. Karyotyping analysis could be made in only 22 patients.