Matrix metalloproteinase-2 expression in laryngeal preneoplastic and neoplastic lesions
PATHOLOGY RESEARCH AND PRACTICE, cilt.197, sa.7, ss.483-486, 2001 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 197 Sayı: 7
- Basım Tarihi: 2001
- Doi Numarası: 10.1078/0344-0338-00115
- Dergi Adı: PATHOLOGY RESEARCH AND PRACTICE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.483-486
- Anahtar Kelimeler: carcinoma in situ, dysplasia, larynx, matrix metalloproteinase, squamous cell carcinoma
- Dokuz Eylül Üniversitesi Adresli: Hayır
Özet
Matrix metalloproteinase-2 (MMP-2), a member of gelatinases, is particularly important in the digestion of nonfibrillary and denaturated collagens; thus, it may play a role in tissue remodeling and in the invasion of malignant cells. The expression of MMP-2 has not yet been described in preneoplastic lesions of the larynx thus far. The purpose of this study was to evaluate whether the expression of MMP-2 plays a role in early laryngeal carcinogenesis.