Anti-inflammatory activity of Anthemis aciphylla var. aciphylla Boiss.
TURKISH JOURNAL OF BIOLOGY, cilt.35, sa.6, ss.757-762, 2011 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 35 Sayı: 6
- Basım Tarihi: 2011
- Doi Numarası: 10.3906/biy-1006-15
- Dergi Adı: TURKISH JOURNAL OF BIOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.757-762
- Anahtar Kelimeler: Anthemis aciphylla, anti-inflammatory activity, carrageenin, paw edema, cotton pellet
- Dokuz Eylül Üniversitesi Adresli: Evet
Özet
Ethanolic (EEAA) and sesquiterpene lactone (SEAA) extracts of the aerial parts of Anthemis aciphylla var. aciphylla Boiss. (Asteraceae) were evaluated for anti-inflammatory activity on carrageenin-induced paw edema (acute model) and cotton pellet-induced granuloma (chronic model) in rats. In carrageenin-induced paw edema, EEAA and SEAA at intraperitoneal doses of 50, 100, and 200 mg/kg dose-dependently inhibited the paw edema. In cotton pellet-induced granuloma, the oral administration of EEAA and SEAA at 50, 100, and 200 mg/kg dosages was also found to significantly inhibit granuloma tissue formation.