The Value of Serum Ischemia Modified Albumin Levels on Diagnosing Pediatric Testicular Torsion and Predicting Testicular Atrophy After Operation


ULUSOY O., Sencan M., Bilen A., ULUSOY E., KÜME T., ATEŞ O., ...Daha Fazla

JOURNAL OF PEDIATRIC EMERGENCY AND INTENSIVE CARE MEDICINE, cilt.12, sa.1, ss.29-34, 2025 (ESCI) identifier

Özet

Introduction: To clinically investigate the value of serum ischemia modified albumin (IMA) levels on diagnosing pediatric testicular torsion (TT) and predicting testicular atrophy after operation. Methods: This prospective case control study was conducted between June 2021 and January 2023. Patients aged 1-18 years who were evaluated for acute scrotum and diagnosed as TT based on clinical and radiological evaluations were included in the study. Demographic data, clinical features, radiological findings, serum IMA levels, operative findings, short and long-term complications, followup were recorded. Results: The serum IMA levels of patients who underwent operation due to TT were statistically significantly higher compared with the control group (p<0.001). Receiver operating characteristic analysis revealed an optimal cut-off point at 18.90 ng/mL for separating the TT group from the control group. When patients who underwent orchiectomy during surgery were compared with those who developed testicular atrophy after detorsion, no statistically significant difference was found in terms of serum IMA levels (p=0.857). Serum IMA levels in patients who underwent orchiectomy during surgery and in patients who developed testicular atrophy after detorsion were significantly higher than in patients without complications (p=0.013 and p=0.012, respectively). Conclusion: In the present clinical study, we found that serum IMA levels are a valuable molecule in the diagnosis of childhood TT, in predicting testicular atrophy, and therefore in the decision for intraoperative orchiectomy.