Does the presence of vesicoureteral reflux affect in vitro uropathogenic E-coli growth rate in urine?

SOYLU A., KARAMAN M., Alaygut D., Camlar S. A., Turkmen M., KAVUKÇU S.

INTERNATIONAL UROLOGY AND NEPHROLOGY, vol.48, no.2, pp.151-154, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 2
  • Publication Date: 2016
  • Doi Number: 10.1007/s11255-015-1168-9
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.151-154
  • Keywords: Vesicoureteral reflux, Uropathogenic Escherichia coli, Urine, Growth rate, TRACT-INFECTION, CHILDREN, UROPLAKINS, BIOLOGY
  • Dokuz Eylül University Affiliated: Yes


Uroepithelial molecules like uroplakins are involved both in the development of urinary tract and in colonization, attachment and invasion of uropathogenic Escherichia coli (UPEC). Uroplakin disorders are also associated with vesicoureteral reflux (VUR). We hypothesized that urine contents, as well as urinary flow, may be altered in VUR, and aimed to determine whether in vitro UPEC growth is increased in urine from the refluxing systems.