TNF-alpha Inhibitors for the Management of Intractable Corneal Melt: Report of Three Cases and Review of the Literature

Utine C. A., Birlik M., Özizmirliler D., Karakaş A., Akbulut B., Durak I.

EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE, vol.47, no.6, pp.372-377, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 47 Issue: 6
  • Publication Date: 2021
  • Doi Number: 10.1097/icl.0000000000000770
  • Journal Name: EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Page Numbers: pp.372-377
  • Keywords: Corneal melting, Infliximab, TNF-alpha inhibitor, PERIPHERAL ULCERATIVE KERATITIS, STEVENS-JOHNSON SYNDROME, RHEUMATOID-ARTHRITIS, BOSTON KERATOPROSTHESIS, CERTOLIZUMAB PEGOL, INFLIXIMAB, THERAPY, METHOTREXATE, PERFORATIONS, EXPRESSION
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objective: To report three consecutive cases with noninfectious corneal melting, whose disease progression could only be halted with tumor necrosis-alpha (TNF-alpha) inhibitor infusion, with a review of the relevant literature.