Increased sleep tendency in jaundiced infants: role of endogenous CO.

ÖZKAN H., Tuzun F., KUMRAL A., Yesilirmak D., DUMAN N.

Medical hypotheses, cilt.71, sa.6, ss.879-80, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 71 Sayı: 6
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.mehy.2008.06.039
  • Dergi Adı: Medical hypotheses
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.879-80
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Carbon monoxide formed from the breakdown of heme to bilirubin is produced at a rate equal to the rate of bilirubin synthesis. During long-term clinical experiences we have observed that jaundiced newborns tend to steep more than the unjaundiced ones. There is no clear evidence about the role of endogenous CO in steep physiology, but increased CO production in jaundiced newborns probably plays rote in increased steep state due to the regulatory effects on steep circadian rhythm and REM-steep, via cholinergic system activation. (C) 2008 Elsevier Ltd. ALL rights reserved.