Role of epigenetic regulatory mechanisms in neonatal hypoxic-ischemic brain injury

KUMRAL, ABDULLAH; Tuzun, FUNDA; TUĞYAN, KAZIM; ÖZBAL, SEDA; YILMAZ, OSMAN; Yesilirmak, Cemile; DUMAN, NURAY; ÖZKAN, HASAN

doi:10.1016/j.earlhumdev.2012.09.016

Role of epigenetic regulatory mechanisms in neonatal hypoxic-ischemic brain injury

KUMRAL A., Tuzun F., TUĞYAN K., ÖZBAL S., YILMAZ O., Yesilirmak C. D., ...Daha Fazla

EARLY HUMAN DEVELOPMENT, cilt.89, sa.3, ss.165-173, 2013 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 89 Sayı: 3
Basım Tarihi: 2013
Doi Numarası: 10.1016/j.earlhumdev.2012.09.016
Dergi Adı: EARLY HUMAN DEVELOPMENT
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.165-173
Anahtar Kelimeler: Newborn, Hypoxic-ischemia, Epigenetic, DNA methylation, Histone methylation, Gene expression, Rat, Apoptosis, Angiogenesis
Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background: DNA methylation and histone modifications are the most identified modifications that selectively activate or inactivate genes that control cell growth, proliferation, and apoptosis.