An electrochemical DNA biosensor for the detection of DNA damage caused by radioactive iodine and technetium

Kara P., Dagdeviren K., Oezsoez M.

TURKISH JOURNAL OF CHEMISTRY, cilt.31, sa.3, ss.243-249, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 3
  • Basım Tarihi: 2007
  • Dergi Adı: TURKISH JOURNAL OF CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.243-249
  • Anahtar Kelimeler: Electrochemistry, DNA damage, Tc-99m, iodine-131
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

A DNA damage process by radioactive iodine (I-131) and technetium (Tc-99m) is described. The procedure relies on a label-free electrochemical DNA biosensor. Fish sperm double stranded DNA was immobilized onto a carbon paste electrode (CPE) by electro deposition and the changes to the guanine oxidation signal were observed upon exposure to radioactive I-131 and Tc-99m by differential pulse voltammetry (DPV).