Molecular characteristics of colorectal hyperplastic polyp subgroups

Unlu M., Uzun E., BENGİ G., SAĞOL Ö., SARIOĞLU S.

TURKISH JOURNAL OF GASTROENTEROLOGY, vol.31, no.8, pp.573-580, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 8
  • Publication Date: 2020
  • Doi Number: 10.5152/tjg.2020.19322
  • Journal Name: TURKISH JOURNAL OF GASTROENTEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.573-580
  • Keywords: Molecular, hyperplastic polyps, colorectal, subgroup, MICROSATELLITE INSTABILITY, CANCER, ADENOCARCINOMA, ADENOMAS, PATHWAY, COLON
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background/Aims: The importance of hyperplastic polyps during colorectal carcinogenesis is appreciated related to the understanding of serrated pathway. The morphologic subtypes of hyperplastic polyps in carcinogenesis and the nomenculature of lesions with both hyperplastic and adenomatous areas are controversial. We aimed to reveal the molecular properties of hyperplastic polyp subtypes and the molecular changes in polyps containing both hyperplastic and adenomatous areas.