Do antihistamines reduce side effects of rapid vancomycin infusion? (Case report) Hizli vankomisin i̇nfüzyonunun yan etkilerini antihistaminikler azaltir mi? (Olgu sunumu)

İYİLİKÇİ KARAOĞLAN L., Tabel Y., Çapar E., ARKAN A.

Turk Anesteziyoloji ve Reanimasyon, cilt.30, sa.5, ss.236-238, 2002 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 5
  • Basım Tarihi: 2002
  • Dergi Adı: Turk Anesteziyoloji ve Reanimasyon
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.236-238
  • Anahtar Kelimeler: Antihistaminikler, Rapid vancomycin infusion
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

In this case report 8 months old male infant in whom V-P shunt surgery was planned for hydrocephalus is presented. Vancomycin 240 mg was administered accidentally intravenously in 1-2 minutes during the operation. Probably due to diphenhydramine (1 mg/kg) administered before vancomycin infusion no symptoms of 'Red Man Syndrome' as hypotension and maculopapolar skin rash occurred. Antihistamines administered before vancomycin infusion may attenuate adverse effects of vancomycin due to histamine release.