Stereological evaluation of the volume and volume fraction of intracranial structures in magnetic resonance images of patients with Alzheimer's disease.

Bas, Orhan; Acer, Niyazi; Mas, NERMİN; Karabekir, HAMİT; Kusbeci, Ozge; Sahin, Bunyamin

doi:10.1016/j.aanat.2008.12.003

Stereological evaluation of the volume and volume fraction of intracranial structures in magnetic resonance images of patients with Alzheimer's disease.

Bas O., Acer N., Mas N. N., Karabekir H. S., Kusbeci O. Y., Sahin B.

Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft, cilt.191, sa.2, ss.186-95, 2009 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 191 Sayı: 2
Basım Tarihi: 2009
Doi Numarası: 10.1016/j.aanat.2008.12.003
Dergi Adı: Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.186-95
Anahtar Kelimeler: Cavalieri principle, Volume estimation, Volume ratio, Magnetic resonance imaging, Stereology, Alzheimer
Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

In this study, we describe and adapt the relevant methods of magnetic resonance (MR) and stereology to estimate total brain volume (TBV), cerebral and cerebellar volume and their volume fractions within the brain. The study included 15 (8 males, 7 females) controls and 15 (8 males, 7 females) patients with Alzheimer's disease. The patients MR images were obtained in both sagittal and axial planes. The volume and volume fraction of the total brain, cerebrum and cerebellum were determined on MR images using the point-counting approach of stereological methods.