Brain atrophy and lesion burden are associated with disability progression in a multiple sclerosis real-world dataset using only T2-FLAIR: The NeuroSTREAM MSBase study

Barnett M., Bergsland N., Weinstock-Guttman B., Butzkueven H., Kalincik T., Desmond P., ...More

NEUROIMAGE-CLINICAL, vol.32, 2021 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 32
  • Publication Date: 2021
  • Doi Number: 10.1016/j.nicl.2021.102802
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals
  • Keywords: Multiple sclerosis, Disability progression, Brain atrophy, Lateral ventricle volume, Lesion burden, Salient central lesion volume, RESONANCE-IMAGING OUTCOMES, GRAY-MATTER ATROPHY, ROUTINE CLINICAL-PRACTICE, RETROSPECTIVE ANALYSIS, RECEIVING FINGOLIMOD, DISEASE-ACTIVITY, NO EVIDENCE, MRI, MS, RELEVANCE
  • Dokuz Eylül University Affiliated: Yes


Background: Methodological challenges limit the use of brain atrophy and lesion burden measures in the followup of multiple sclerosis (MS) patients on clinical routine datasets.