The protective effects of dexmedetomidine against apoptosis in retinal ischemia/reperfusion injury in rats
CUTANEOUS AND OCULAR TOXICOLOGY, cilt.33, sa.4, ss.283-288, 2014 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 33 Sayı: 4
- Basım Tarihi: 2014
- Doi Numarası: 10.3109/15569527.2013.857677
- Dergi Adı: CUTANEOUS AND OCULAR TOXICOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.283-288
- Anahtar Kelimeler: Apoptosis, dexmedetomidine, retinal ischemia/reperfusion injury
- Dokuz Eylül Üniversitesi Adresli: Evet
Özet
Objective: Dexmedetomidine is an alpha 2 adrenoceptor agonist and can be used for postoperative sedation, analgesia and anesthesia-sparing properties. Furthermore, the neuroprotective effects against ischemia/reperfusion (I/R) injury in the central nervous system have been shown in experimental studies. This study aimed to investigate the protective effects of dexmedetomidine against apoptosis in retinal I/R injury in the rat.