The protective effects of dexmedetomidine against apoptosis in retinal ischemia/reperfusion injury in rats
CUTANEOUS AND OCULAR TOXICOLOGY, vol.33, no.4, pp.283-288, 2014 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 33 Issue: 4
- Publication Date: 2014
- Doi Number: 10.3109/15569527.2013.857677
- Journal Name: CUTANEOUS AND OCULAR TOXICOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.283-288
- Keywords: Apoptosis, dexmedetomidine, retinal ischemia/reperfusion injury
- Dokuz Eylül University Affiliated: Yes
Abstract
Objective: Dexmedetomidine is an alpha 2 adrenoceptor agonist and can be used for postoperative sedation, analgesia and anesthesia-sparing properties. Furthermore, the neuroprotective effects against ischemia/reperfusion (I/R) injury in the central nervous system have been shown in experimental studies. This study aimed to investigate the protective effects of dexmedetomidine against apoptosis in retinal I/R injury in the rat.