MEASUREMENT AND CORRELATION OF INDICES OF INSULIN RESISTANCE IN PATIENTS ON PERITONEAL DIALYSIS


King-Morris K. R., DEĞER S. M., Hung A. M., Egbert P. A., Ellis C. D., Graves A., ...More

PERITONEAL DIALYSIS INTERNATIONAL, vol.36, no.4, pp.433-441, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 4
  • Publication Date: 2016
  • Doi Number: 10.3747/pdi.2013.00296
  • Journal Name: PERITONEAL DIALYSIS INTERNATIONAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.433-441
  • Keywords: Metabolism, atherosclerosis, insulin resistance, ESRD, dialysis, leptin-adiponectin ratio, HOMA-IR, CHRONIC KIDNEY-DISEASE, METABOLIC SYNDROME, SENSITIVITY, HOMEOSTASIS, PREDICTOR
  • Dokuz Eylül University Affiliated: No

Abstract

Background: Insulin resistance (IR) is common in maintenance dialysis patients and is associated with excess mortality. Hyperinsulinemic euglycemic glucose clamp (HEGC) is the gold standard for measuring IR. There are limited studies using HEGC for comparison to other indirect indices of IR in peritoneal dialysis (PD) patients, nor have there been direct comparisons between patients receiving PD and those on maintenance hemodialysis (MHD) with regard to severity of IR, methods of measurement, or factors associated with the development of IR.