Combined Analysis of the Prevalence of Drug-Resistant Hepatitis B Virus in Antiviral Therapy-Experienced Patients in Europe (CAPRE)

Hermans, Lucas; Svicher, Valentina; Pas, Suzan; Salpini, Romina; Alvarez, Marta; Ben Ari, Ziv; Boland, Greet; Bruzzone, Bianca; Coppola, Nicola; Seguin-Devaux, Carole; Dyda, Tomasz; Garcia, Federico; Kaiser, Rolf; Kose, ŞÜKRAN; Krarup, Henrik; Lazarevic, Ivana; Lunar, Maja; Maylin, Sarah; Micheli, Valeria; Mor, Orna; Paraschiv, Simona; Paraskevis, Dimitrios; Poljak, Mario; Puchhammer-Stoeckl, Elisabeth; Simon, Francois; Stanojevic, Maja; Stene-Johansen, Kathrine; Tihic, Nijaz; Trimoulet, Pascale; Verheyen, Jens; Vince, Adriana; Weis, Nina; Yalcinkaya, Tulay; Lepej, Snjezana; Perno, Carlo; Boucher, Charles; Wensing, Annemarie

doi:10.1093/infdis/jiv363

Combined Analysis of the Prevalence of Drug-Resistant Hepatitis B Virus in Antiviral Therapy-Experienced Patients in Europe (CAPRE)

Atıf İçin Kopyala

Hermans L. E., Svicher V., Pas S. D., Salpini R., Alvarez M., Ben Ari Z., ...Daha Fazla

JOURNAL OF INFECTIOUS DISEASES, cilt.213, sa.1, ss.39-48, 2016 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 213 Sayı: 1
Basım Tarihi: 2016
Doi Numarası: 10.1093/infdis/jiv363
Dergi Adı: JOURNAL OF INFECTIOUS DISEASES
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.39-48
Anahtar Kelimeler: antiviral drug resistance, genotypic resistance testing, hepatitis B virus, nucleos(t)ide analogs, COST-EFFECTIVENESS, REDUCED ANTIGENICITY, LAMIVUDINE TREATMENT, POLYMERASE GENE, PRIOR EXPOSURE, ENTECAVIR, MUTATIONS, TENOFOVIR, HBV, CONSEQUENCE
Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

European guidelines recommend treatment of chronic hepatitis B virus infection (CHB) with the nucleos(t)ide analogs (NAs) entecavir or tenofovir. However, many European CHB patients have been exposed to other NAs, which are associated with therapy failure and resistance. The CAPRE study was performed to gain insight in prevalence and characteristics of NA resistance in Europe.