Effect of nitrergic system on colonic motility in a rat model of irritable bowel syndrome

Temiz, Tijen; Demir, Omer; Simsek, Fatma; Kaplan, Yusuf; Bahçeci, Selen; Karadas, Baris; Çelik, ASLI; Köylüoğlu, Gökhan

doi:10.4103/0253-7613.186189

Effect of nitrergic system on colonic motility in a rat model of irritable bowel syndrome

Temiz T., Demir O., Simsek F., Kaplan Y. C., Bahçeci S., Karadas B., ...More

INDIAN JOURNAL OF PHARMACOLOGY, vol.48, no.4, pp.424-429, 2016 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 48 Issue: 4
Publication Date: 2016
Doi Number: 10.4103/0253-7613.186189
Journal Name: INDIAN JOURNAL OF PHARMACOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.424-429
Keywords: Distal colon, immunohistochemistry, irritable bowel syndrome, nitric oxide synthase
Dokuz Eylül University Affiliated: Yes

Abstract

Aim: The aim of this study is to investigate whether nitric oxide (NO)-mediated colonic motility was altered in rat irritable bowel syndrome (IBS) model, using different isoforms of NO-synthase (NOS) inhibitors.