Effect of nitrergic system on colonic motility in a rat model of irritable bowel syndrome


Temiz T., Demir O., Simsek F., Kaplan Y. C., Bahçeci S., Karadas B., ...Daha Fazla

INDIAN JOURNAL OF PHARMACOLOGY, cilt.48, sa.4, ss.424-429, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 4
  • Basım Tarihi: 2016
  • Doi Numarası: 10.4103/0253-7613.186189
  • Dergi Adı: INDIAN JOURNAL OF PHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.424-429
  • Anahtar Kelimeler: Distal colon, immunohistochemistry, irritable bowel syndrome, nitric oxide synthase, NITRIC-OXIDE SYNTHASE, VISCERAL HYPERSENSITIVITY, IN-VITRO, DISEASE, DIARRHEA, RECEPTOR, PAIN
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Aim: The aim of this study is to investigate whether nitric oxide (NO)-mediated colonic motility was altered in rat irritable bowel syndrome (IBS) model, using different isoforms of NO-synthase (NOS) inhibitors.