JOURNAL OF PERIODONTOLOGY, vol.91, no.10, pp.1339-1347, 2020 (SCI-Expanded)
Background Cystic fibrosis (CF) is a life-threatening chronic inflammatory disease in children due to respiratory complications. Saliva could serve as a reservoir of bacterial colonization and potentially reflect systemic inflammation. This study investigated whether salivary triggering receptor expressed on myeloid cells 1 (TREM-1), peptidoglycan recognition protein 1 (PGLYRP1), interleukin (IL)-1 beta, and calprotectin are associated with CF or reflect concomitant gingival inflammation.