Salivary biomarkers in the context of gingival inflammation in children with cystic fibrosis

Yucel Z. P. K., Silbereisen A., EMİNGİL G., Tokgoz Y., Kose T., Sorsa T., ...Daha Fazla

JOURNAL OF PERIODONTOLOGY, cilt.91, sa.10, ss.1339-1347, 2020 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 91 Sayı: 10
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1002/jper.19-0415
  • Dergi Adı: JOURNAL OF PERIODONTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database, DIALNET
  • Sayfa Sayıları: ss.1339-1347
  • Anahtar Kelimeler: biomarkers, calprotectin, cystic fibrosis, gingivitis, saliva, TREM-1 protein
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Background Cystic fibrosis (CF) is a life-threatening chronic inflammatory disease in children due to respiratory complications. Saliva could serve as a reservoir of bacterial colonization and potentially reflect systemic inflammation. This study investigated whether salivary triggering receptor expressed on myeloid cells 1 (TREM-1), peptidoglycan recognition protein 1 (PGLYRP1), interleukin (IL)-1 beta, and calprotectin are associated with CF or reflect concomitant gingival inflammation.