Anestezi Dergisi, cilt.10, sa.1, ss.37-40, 2002 (Scopus)
In this study, our object was to observe the effects of using Laryngeal Mask Airway (LMA) with propofol and midazolam on the hemodynamics and intraocular pressure (IOP). Fifty patients in ASA risk groups I and II that would undergone urological or general surgical procedures. In group I (n=25) patients received midazolam 0.25-0.1 mg .kg-1 i.v. and alfentanyl 10 mg kg-1 i.v. for induction and them. LMA was placed. Maintenance was performed by an infusion of midazolam 0.05 mg kg-1 h-1. In group II (n=25) patients received propofol 2-3 mg kg-1 i.v. and alfentanyl 10 mg kg-1 i.v. for induction and LMA was placed. Maintenance was provided by infusion of propofol 2-3 mg kg-1 h-1. IOP (mmHg), mean arterial pressure (MAP) and heart rate (HR) were recorded just before induction (T1) after the placement of LMA (T2), 5 minutes after the induction (T3) and after the displacement of LMA (T4). IOP was measured in the right eye with after the administration of local anesthetic oxybuprocain HCl 0.4% Schiöetz tonometry. During the group comparisons, HR and MAP values were found to be significantly low at T2, T3 and T4 in propofol group when compared with group I (p<0.05). IOP values were significantly decrease at T2 and T4 measurements (p<0.001) in propofol group. No complication developed during removel of LMA. In our study; propofol in LMA administration decreases the IOP however midazolam increases it minimal but this increases is not in the pathological values. In LMA administiration midazolam stabilizes the cardiovascular system better than propofol. For this reason, in the cases undergoing to ophthalmic operations whom are not in haemodynamic stabilization and have to keep the IOP steady, midazolam can be a good alternative.