CLINICAL FEATURES, TREATMENT RESPONSES, AND OUTCOME OF CHILDREN WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA

Demircioglu F., Saygi M., YILMAZ Ş., ÖREN H., Irken G.

PEDIATRIC HEMATOLOGY AND ONCOLOGY, cilt.26, sa.7, ss.526-532, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 7
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1080/08880010903044540
  • Dergi Adı: PEDIATRIC HEMATOLOGY AND ONCOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.526-532
  • Anahtar Kelimeler: high-dose methylprednisolone, immune thrombocytopenic purpura, intravenous immunoglobulin, vaccination, INTRAVENOUS IMMUNOGLOBULIN, MEGADOSE METHYLPREDNISOLONE, IMMUNE THROMBOCYTOPENIA, CHILDHOOD, MANAGEMENT, ITP
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

The authors investigated demographics, clinical and laboratory features, treatment responses, and outcomes of 93 children (median age 5 years) admitted for idiopathic thrombocytopenic purpura (ITP). The therapy responses of high-dose methylprednisolone (HDMP) (n = 77) and intravenous immunoglobulin (IVIG) (n = 10) treatments were similar. None of the patients with hemorrhage died. Fifteen patients (16.1%) had progressed into chronic ITP. Seven infants had a probable relationship with vaccination; none of these infants progressed into chronic ITP. In conclusion, the overall prognosis in childhood ITP is good. The therapy responses of HDMP and IVIG treatments are similar. Also, ITP cases who havw vaccination history have a benign course.