COVID-19’da biyokimyasal ve hematolojik parametreler


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Gürsoy Doruk Ö., Örmen M., Tuncel E. P.

J DEU Med, sa.35(Özel Sayı 1), ss.71-80, 2021 (Hakemli Dergi)

  • Yayın Türü: Makale / Derleme
  • Basım Tarihi: 2021
  • Doi Numarası: 10.5505/deutfd.2021.35403
  • Dergi Adı: J DEU Med
  • Derginin Tarandığı İndeksler: TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.71-80
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

There is extensive research related to the changes in the hematological and biochemical tests in COVID- infection. The complete blood count, especially leucocyte, lymphocyte and thrombocyte counts became prominent among the routine clinical chemistry tests since this is a infectious process and these tests are easy to perform. Besides, interleukins, C-reactive protein, erithrocyte sedimentation rate, procalcitonin, ferritin were used widely to assess the inflamatory process and the “cytokine storm”. Some parameters are used to evaluate the complications related to the liver, kidneys and the heart. Hypercoagulopathy and thrombosis werecommon in this infection and the major reason for many complications seen in COVID-19. Creatine kinase, cardiac troponins, myoglobin were used to assess cardiac status; aspartat aminotransferase, albumin, lactate dehydrogenase were used broadly to assess liver function and fibrin degradation products, activated partial thromboplastin time and D-dimer were used to determine the thrombotic state.
In this review article, we aimed to address the parameters that are important in the diagnosis, treatment and prognosis of COVID-19, discuss their diagnostic and prognostic efficiency and their value in risk stratification.

Keywords: COVID-19, laboratory tests, biochemistry, hematology, prognosis