High expression of mesothelin in advanced serous ovarian cancer is associated with poor prognosis

Yildiz Y., Kabadayi G., Yigit S., KÜÇÜKZEYBEK Y., ALACACIOĞLU A., Varol U., ...More

JOURNAL OF BUON, vol.24, no.4, pp.1549-1554, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 4
  • Publication Date: 2019
  • Journal Name: JOURNAL OF BUON
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1549-1554
  • Keywords: mesothelin, serous ovarian cancer, overall survival, prognosis, PROLONGED PATIENT SURVIVAL, MONOCLONAL-ANTIBODY, SERUM MESOTHELIN, OVEREXPRESSION, STATISTICS, DIAGNOSIS, MARKER, TARGET, STAGE, K1
  • Dokuz Eylül University Affiliated: Yes

Abstract

Purpose: Mesothelin is a cell surface glycoprotein which is highly expressed in various types of epithelial cancers. Its expression level is associated with poor prognosis in many cancer types. The aim this study was to evaluate the association of the level of mesothelin expression with clinicopathological characteristics and its prognostic significance in patients with advanced serous ovarian cancer (SOC).