Akademik Veri Yönetim Sistemi
Journal of Basic and Clinical Health Sciences, cilt.9, sa.1, ss.182-187, 2025 (ESCI)
Purpose: Partial splenic embolization is a common treatment for hypersplenism in patients with cirrhosis. In this investigation, we evaluated the effectiveness and safety of partial splenic embolization in patients with cirrhosis. Materials and Methods: We retrospectively investigated 17 patients with hypersplenism secondary to cirrhosis who underwent partial splenic embolization. Following partial splenic embolization, peripheral blood cell counts were measured at regular intervals over a period of twelve months. Post-procedural complications were recorded. Results: This study included 17 individuals, with a mean age of 54.5 ± 10 years. Hemoglobin, platelet, neutrophil, lymphocyte, and white blood cell counts showed statistically significant increases. When compared to the pre- procedure levels at each time point (pre-procedure vs. 1st day p<0.001; pre-procedure vs. 1st week p<0.001; pre- procedure vs. 1st month p<0.001; pre-procedure vs. 6th month p<0.001; pre-procedure vs. 1st year p<0.001). The most common complication was post-embolization syndrome (88.2%), which was managed with conservative treatment. One patient died of esophageal variceal bleeding. Conclusion: Partial splenic embolization improves long-term hematological parameters with manageable side effects.