Peripheral Blood Cell Changes And Outcomes After Partial Splenic Embolization For Hypersplenism İn Cirrhotic Patients
Journal of Basic and Clinical Health Sciences, vol.9, no.1, pp.182-187, 2025 (ESCI, TRDizin)
- Publication Type: Article / Article
- Volume: 9 Issue: 1
- Publication Date: 2025
- Doi Number: 10.30621/jbachs.1561027
- Journal Name: Journal of Basic and Clinical Health Sciences
- Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
- Page Numbers: pp.182-187
- Keywords: Partial splenic embolization, cirrhosis, hypersplenism
- Open Archive Collection: AVESIS Open Access Collection
- Dokuz Eylül University Affiliated: Yes
Abstract
Purpose: Partial splenic embolization is a common treatment for hypersplenism in patients with cirrhosis. In this investigation, we evaluated the effectiveness and safety of partial splenic embolization in patients with cirrhosis. Materials and Methods: We retrospectively investigated 17 patients with hypersplenism secondary to cirrhosis who underwent partial splenic embolization. Following partial splenic embolization, peripheral blood cell counts were measured at regular intervals over a period of twelve months. Post-procedural complications were recorded. Results: This study included 17 individuals, with a mean age of 54.5 ± 10 years. Hemoglobin, platelet, neutrophil, lymphocyte, and white blood cell counts showed statistically significant increases. When compared to the pre- procedure levels at each time point (pre-procedure vs. 1st day p<0.001; pre-procedure vs. 1st week p<0.001; pre- procedure vs. 1st month p<0.001; pre-procedure vs. 6th month p<0.001; pre-procedure vs. 1st year p<0.001). The most common complication was post-embolization syndrome (88.2%), which was managed with conservative treatment. One patient died of esophageal variceal bleeding. Conclusion: Partial splenic embolization improves long-term hematological parameters with manageable side effects.