In Vitro Evaluation of Tc-99m Radiopharmaceuticals for Gastric Emptying Studies

Ertay T., Doğan A. S., Durak H.

molecular imaging and radionuclide therapy, vol.23, no.1, pp.21-24, 2014 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 1
  • Publication Date: 2014
  • Doi Number: 10.4274/mirt.75047
  • Journal Name: molecular imaging and radionuclide therapy
  • Page Numbers: pp.21-24
  • Keywords: Gastric emptying, scintigraphy, radiopharmaceutical, technetium, Tc-99m sulfur colloid, nanoparticles, Tc-99m-MAA, Tc (99m)-DTPA
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objective: Gastrointestinal motility and functional motility disorders causing either delayed or accelerated gastric emptying (GE) may result in similar symptoms including nausea, vomiting, early satiety, fullness, bloating, and abdominal discomfort or pain. Hence, it is important to evaluate patients for both rapid and delayed GE in the same test. The gold standard technique to measure GE is scintigraphy by radiolabeled test meals. The aim of this study was to test alternative Tc-99m agents to label eggs as the solid meal and compare to Tc-99m sulfur colloid (SC) for gastric emptying studies.