In Vitro Evaluation of Tc-99m Radiopharmaceuticals for Gastric Emptying Studies

Ertay T., Doğan A. S., Durak H.

molecular imaging and radionuclide therapy, cilt.23, sa.1, ss.21-24, 2014 (Hakemli Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 1
  • Basım Tarihi: 2014
  • Doi Numarası: 10.4274/mirt.75047
  • Dergi Adı: molecular imaging and radionuclide therapy
  • Sayfa Sayıları: ss.21-24
  • Anahtar Kelimeler: Gastric emptying, scintigraphy, radiopharmaceutical, technetium, Tc-99m sulfur colloid, nanoparticles, Tc-99m-MAA, Tc (99m)-DTPA
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: Gastrointestinal motility and functional motility disorders causing either delayed or accelerated gastric emptying (GE) may result in similar symptoms including nausea, vomiting, early satiety, fullness, bloating, and abdominal discomfort or pain. Hence, it is important to evaluate patients for both rapid and delayed GE in the same test. The gold standard technique to measure GE is scintigraphy by radiolabeled test meals. The aim of this study was to test alternative Tc-99m agents to label eggs as the solid meal and compare to Tc-99m sulfur colloid (SC) for gastric emptying studies.