Renal cell carcinoma associated immunosuppressive therapy: a case report with Wegener's granulomatosis

DEĞER S. M., Mutluay R., Ebinc F. A., Arinsoy T., Sindel S.

RHEUMATOLOGY INTERNATIONAL, cilt.30, sa.1, ss.119-121, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 1
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1007/s00296-009-0911-x
  • Dergi Adı: RHEUMATOLOGY INTERNATIONAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.119-121
  • Anahtar Kelimeler: Wegener's granulomatosis (WG), Renal cell carcinoma (RCC), Cyclophosphamide, Azathioprine, Vasculitis, CYCLOPHOSPHAMIDE, MALIGNANCIES, TRIAL
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Development of uroepithelial tumors after cyclophosphamide and azathioprine therapy in Wegener's granulomatosis (WG) have been reported in the literature but renal cell carcinoma (RCC), rarely. RCC associated with WG has been previously reported in a few cases. Most of them have simultaneous diseases. Here, we report a case, which developed RCC 8 years after initiation of WG. Long-term immunosuppressive treatment is a risk factor for the development of malignancies; it should be suggested that RCC in our patient might be due to immunosuppressive therapy.