Akademik Veri Yönetim Sistemi
6. Uluslararası Sağlık Bilimleri ve Yaşam Kongresi, Burdur, Türkiye, 2 - 05 Mart 2023, ss.605
Background: Intraosseous defects resulting from periodontal destruction can be treated with
various materials. Intrabony defects can be treated through various treatment approaches,
including guided tissue regeneration using barrier membranes, various types or combinations
of grafting materials, enamel matrix proteins, and autologous platelet concentrates. Aim: To
treat deep intraosseous defect as a result of periodontal destruction with titanium-prepared
platelet-rich fibrin (T-PRF). Methods: A 53-year-old female patient with hypertension applied
to our clinic with the complaints of abscess, pain or bleeding constantly developing between
teeth 42 and 43. As a result of clinical and radiographic examination, periodontal abscess and
intraosseous defect reaching up to the apical were detected. After phase-1 treatment, T-PRF
was placed in the intraosseous defect area with flap surgery. Results: It was noted that no
abscess, pain and bleeding symptoms developed during the postoperative period. Three months
after the operation, the beginning of bone regeneration was detected on the radiograph in the
apical 2/3 part of the tooth. Discussion and Conclusion: Growth factors released from T-PRF
stimulate surrounding osteoblasts, fibroblasts and periodontal ligament cells with their chemoattractant properties. It is thought that T-PRF, which is used in the regeneration of intraosseous
defects, provides radiographic and clinical improvement in the early period with its anti-inflammatory and regenerative cell capacity.
Keywords: titanium-platelet rich fibrin, intra-osseos defect, bone regeneration