Akademik Veri Yönetim Sistemi
VIRAL HEPATIT DERGISI-VIRAL HEPATITIS JOURNAL, cilt.11, sa.2, ss.70-75, 2006 (ESCI)
It has been suggested that medical and/or surgical procedures may have important role for transmission of hepatitis B and hepatitis C viruses in our country. Patients who have chronic lung diseases such as chronic obstructive lung disease, asthma and interstitial pulmonary disease are frequently hospitalized and therefore frequently expose to nosocomial infectious agents. In this study we aimed to determine seroprevalences of HBV and HCV in chronic lung diseases and also to find out whether the frequent hospitalization is a risk factor for infection by investigating the possible relation between disease duration and hepatitis B and C infection. A totaly 174 patients diagnosed as chronic lung disease were included in the study. The data including HBsAg, anti-HBs, anti-HCV [EIA (Abbott Axsym)], and the duration of lung disease were collected retrospectively from the medical records of the patients. One hundred patients (57.5%) were male and 74 patients (42.5%) were female. The seroprevalence rates were compared with those of blood donors. The mean age was 64.9 11.5 years. The mean duration of chronic lung disease was 11.8 +/- 9.1 years (range 140 years). HBsAg, anti-HBs and anti-HCV were found to be positive in 5.7% (10/174), 43.2% (73/169), 6.7% (11/164), respectively. Although there was no correlation between the duration of chronic lung disease and hepatitis B infection, a statistically significant correlation between the duration of disease and hepatitis C infection was determined. According to our results, the prevalence of hepatitis B infection in patients with chronic lung diseases were not different from the normal population. However the prevalence of HCV infection was higher than the mean prevalence rate of healthy Turkish people and also than the rates found in blood donors (p< 0.001). In addition to these findings, as the anti-HCV positivity increased with the duration of disease, nosocomial transmission was thought be an important factor for HCV transmission in chronic lung diseases.