The 7th Biennial Schizophrenia International Research Society Conference, Florence, Italy, 6 - 10 April 2022, pp.1-2, (Summary Text)
Background
Social
capital is thought to represent an environmental influence impacting risk of psychotic
disorder. This study aims to investigate the association between
neighbourhood-level social capital and clinical transitions within the spectrum
of psychosis.
Methods
2175
participants, representative of a community-based population, were assessed
twice (6-years apart) to determine their position within an extended psychosis
spectrum: no symptoms, subclinical psychotic experiences (PE), clinical PE,
psychotic disorder (PD). A variable representing change between baseline (T1)
and follow-up (T2) assessment was constructed. Four dimensions of social
capital (informal social control, social disorganisation, social cohesion and
trust, cognitive social capital) were assessed at baseline in an independent
sample, and the measures were aggregated to the neighbourhood level.
Associations between the variable representing psychosis spectrum change from
T1 to T2 and the social capital variables were investigated.
Results
Lower
levels of neighbourhood-level social disorganization, meaning higher levels of
social capital, reduced the risk of clinical PE onset (OR=0.300; z=-2.75;
p=0.006), persistence of clinical PE (OR=0.314; z=-2.36; p=0.018) and also the
transition to PD (OR=0.136; z=-2.12; p=0.034). The other social capital
variables were not associated with changes from T1 to T2.
Discussion
Neighbourhood-level
social disorganisation may impact the risk of psychosis expression. Whilst
replication of this finding is required, it may point to level of social disorganisation
as a public health target moderating population psychosis risk.