Genetic causes of syndromic and non-syndromic autism


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ÇAĞLAYAN A. O.

DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, cilt.52, sa.2, ss.130-138, 2010 (SCI-Expanded) identifier identifier identifier

Özet

AIMS Over the past decade, genetic tests have become available for numerous heritable disorders, especially those whose inheritance follows the Mendelian model. Autism spectrum disorders (ASDs) represent a group of developmental disorders with a strong genetic basis. During the past few years, genetic research in ASDs has been successful in identifying several vulnerability loci and a few cytogenetic abnormalities or single-base mutations implicated in the causation of autism.