Genetic causes of syndromic and non-syndromic autism


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ÇAĞLAYAN A. O.

DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, cilt.52, sa.2, ss.130-138, 2010 (SCI-Expanded) identifier identifier

Özet

AIMS Over the past decade, genetic tests have become available for numerous heritable disorders, especially those whose inheritance follows the Mendelian model. Autism spectrum disorders (ASDs) represent a group of developmental disorders with a strong genetic basis. During the past few years, genetic research in ASDs has been successful in identifying several vulnerability loci and a few cytogenetic abnormalities or single-base mutations implicated in the causation of autism.