Convergence spasm due to aquaporin-positive neuromyelitis optica spectrum disorder


Özçelik P., Tanriverdizade T., MEN S., Akdal G.

eNeurologicalSci, cilt.7, ss.7-8, 2017 (Scopus) identifier identifier

  • Yayın Türü: Makale / Kısa Makale
  • Cilt numarası: 7
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1016/j.ensci.2017.03.001
  • Dergi Adı: eNeurologicalSci
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.7-8
  • Anahtar Kelimeler: Aquaporin 4 antibody, Convergence spasm, Neuromyelitis optica
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

© 2017 The Author(s)A female 27 presented with nausea and diplopia for 1 week. On examination she had normal vertical gaze but would develop convergence with miosis whenever she made horizontal saccades. Pupils were 6 mm and unreactive to light. MRI showed extensive hyperintensity in the dorsal midbrain and thalamus. Spinal MRI and CSF were both normal. Serum aquaporin-4-antibody was positive. She was treated with steroids and plasmapheresis and after 3 months convergence spasm resolved but pupils remained unreactive. Neuromyelitis optica often presents with brainstem signs, rarely a dorsal midbrain syndrome. Convergence spasm is occasionally of organic neurologic origin.