Antithrombin III pretreatment reduces neutrophil recruitment into the lung in a rat model of abdominal sepsis.

Koca U., Olguner Ç. G., Ozkardesler S., Karci A., Coker C., Tuncel P., ...Daha Fazla

Acta anaesthesiologica Scandinavica, cilt.49, sa.2, ss.203-8, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 2
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1111/j.1399-6576.2004.00567.x
  • Dergi Adı: Acta anaesthesiologica Scandinavica
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.203-8
  • Anahtar Kelimeler: antithrombin, sepsis, anti-inflammatory, prostacyclin, activated leukocytes, heparin-like glycosaminoglycans, ANIMAL-MODELS, SEPTIC SHOCK, CECAL LIGATION, INJURY, PROSTACYCLIN, INFLAMMATION, COAGULATION, PROTECTION, PREVENTS, EFFICACY
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background: Antithrombin III (AT III) is a serine protease inhibitor and the mechanism of its anti-inflammatory action is still not understood. In the present study, we aimed to investigate the anti-inflammatory action of AT III on lung injury in a rat model of sepsis.