Antithrombin III pretreatment reduces neutrophil recruitment into the lung in a rat model of abdominal sepsis.

Koca, U; Olguner, ÇİMEN; Ozkardesler, SEVDA; Karci, A; Coker, ŞADİYE; Tuncel, EMİNE; Tasdogen, A; Duru, S; Ulukus, EMİNE; Elar, Z

doi:10.1111/j.1399-6576.2004.00567.x

Antithrombin III pretreatment reduces neutrophil recruitment into the lung in a rat model of abdominal sepsis.

Koca U., Olguner Ç. G., Ozkardesler S., Karci A., Coker C., Tuncel P., ...Daha Fazla

Acta anaesthesiologica Scandinavica, cilt.49, sa.2, ss.203-8, 2005 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 49 Sayı: 2
Basım Tarihi: 2005
Doi Numarası: 10.1111/j.1399-6576.2004.00567.x
Dergi Adı: Acta anaesthesiologica Scandinavica
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.203-8
Anahtar Kelimeler: antithrombin, sepsis, anti-inflammatory, prostacyclin, activated leukocytes, heparin-like glycosaminoglycans
Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background: Antithrombin III (AT III) is a serine protease inhibitor and the mechanism of its anti-inflammatory action is still not understood. In the present study, we aimed to investigate the anti-inflammatory action of AT III on lung injury in a rat model of sepsis.