GYNECOLOGY AND PELVIC MEDICINE, cilt.6, 2023 (ESCI)
Background and Objective: To evaluate and write a narrative review of the literature about the meaning of uterine leiomyomas and their fate during pregnancy, on the other, to which extent these tumors are capable of affecting pregnancy outcomes. Nowadays, it is commonly accepted that fibroids can cause slight or no increased risk fo bad obstetric outcome. Although decreased uterine distensibility or mechanical obstruction may explain some adverse outcomes, the precise mechanism by which uterine fibroids induce obstetric complications is not clear. Methods: A narrative review of the literature to gather the researches about the fibroid and pregnancy coexistence with the pregnancy outcomes by searching computerized databases, hand searches, and authoritative texts. Key Content and Findings: An overview of the fibroids and pregnancy coexistence were systematically examined. The behavior of the fibroids during the early and late pregnancy periods was discussed. Studies that advocate the fibroid presence has a negative effect on the early and late pregnancy processes, and studies that against to these outcomes were mentioned. The reported complications and the management options of these complications were discussed. At last, besides the delivery timing and options, the fibroid treatment options during the pregnancy period were also discussed. Conclusions: Due to the different scenarios on the pregnancy outcomes with the coexistence of fibroids and pregnancy. This narrative review provides a vision for the clinicians in both having information about the meaning of the fibroids during the pregnancy period and having information for providing counseling to couples who wish to have a pregnancy or who are waiting a baby at any gestational weeks.