Abstracts of the 20th Turkish Neuroscience Congress 19–23 October 2022, Istanbul, Türkiye
Anatomy, cilt.16, sa.3, ss.225, 2022 (Hakemli Dergi)
- Yayın Türü: Makale / Özet
- Cilt numarası: 16 Sayı: 3
- Basım Tarihi: 2022
- Doi Numarası: 10.2399/ana.22.003s
- Dergi Adı: Anatomy
- Sayfa Sayıları: ss.225
- Dokuz Eylül Üniversitesi Adresli: Evet
Özet
Objective: Cognitive fatigue (CF) is defined as decreased performance at sustained attention task and used as a follow-up test for some of the neurological diseases. On the other hand, the assessment of CF mostly relies on self-reports, and it is a limitation to measure CF objectively. Functional Near Infrared Spectroscopy (fNIRS) shows prefrontal oxyhemoglobin levels altering by function. Paced Auditory Serial Addition Test (PASAT) is a commonly used cognitive test, known to cause cognitive fatigue. Our aim was to establish an objective CF measurement with fNIRS during PASAT. Methods: In our study, seven (7) male volunteers between the ages of 16−22 performed the PASAT test between 09:00 and 12:00 in the presence of an observer. Prefrontal oxyhemoglobin levels were recorded by fNIRS during whole PASAT performance. In the first and last 30 seconds of the PASAT performance, oxyhemoglobin levels were analyzed with the matched T test, the change in correct response was analyzed with the nonparametric Wilcoxon Test, and the relationship between the two parameters was analyzed with the Spearman correlation test. Results: Prefrontal cortex oxyhemoglobin levels of the last part of PASAT were found significantly higher than the first part (p<0.01). The correct answers at the last part of the PASAT were lower than the first part (p=0.05). Negative correlation was observed in the correlation analyzes of these two parameters, but it was not found to be statistically significant (r=-0.5, p>0.05). Conclusion: In this preliminary study, high oxyhemoglobin levels by fNIRS measurement appear to be associated with an increase in false answers during PASAT. In future studies, the measurement of cognitive fatigue via fNIRS could be an objective method to evaluate or follow-up the cases with different cognitive levels.