State of the art in germ cell tumor imaging

SEÇİL M., ALTAY C., BAŞARA AKIN I.

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, vol.34, no.3, pp.156-164, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 3
  • Publication Date: 2016
  • Doi Number: 10.1016/j.urolonc.2015.06.017
  • Journal Name: UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.156-164
  • Keywords: Germ cell tumor, Testis cancer, Ultrasonography, Computed tomography, Magnetic resonance imaging, POSITRON-EMISSION-TOMOGRAPHY, TESTICULAR MICROLITHIASIS, POSTCHEMOTHERAPY SEMINOMA, TESTIS, ELASTOGRAPHY, LESIONS, ULTRASONOGRAPHY, ULTRASOUND, GUIDELINES, DIAGNOSIS
  • Dokuz Eylül University Affiliated: Yes

Abstract

Germ cell tumors (GCTs) are the most common tumors of the testis and arise from germinal epithelium cells in the seminiferous tubules. All GCTs show malignant behavior and frequently metastasize. The diagnosis of GCTs depends on the clinical manifestations, laboratory parameters, preoperative imaging features, and tissue biomarkers. Ultrasonography and Doppler ultrasonography are the primary imaging modalities used to evaluate testicular masses. Sonoelastography is a diagnostic tool that can measure the stiffness of tissue and may differentiate between benign and malignant tumors of testis. Magnetic resonance imaging of the scrotum may be used as an additional tool, which may provide additional information owing to its high soft tissue contrast discrimination capability. Computed tomography of the thorax and abdomen and positron emission tomography/computed tomography are used for staging of the disease and for follow-up after treatment. (C) 2016 Elsevier Inc. All rights reserved.