Corticosteroid Responsive Sarcoidosis with Multisystemic Involvement Years after Initial Diagnosis: A Lymphoma Mimicker on 18-FDG PET/CT

Acar T., SAVAŞ R., Kocacelebi K., UÇAN E. S.

JOURNAL OF CLINICAL IMAGING SCIENCE, vol.5, 2015 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 5
  • Publication Date: 2015
  • Doi Number: 10.4103/2156-7514.161850
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Keywords: Computed tomography, lymphoma, positron-emission tomography, sarcoidosis
  • Dokuz Eylül University Affiliated: Yes


Sarcoidosis is a chronic multisystemic inflammatory disease characterized by noncaseating epithelioid cell granulomas. 18-Fluorodeoxyglucose positron-emission tomography/computer tomography (FDG-PET/CT) is increasingly used in routine clinical practice to assess active sarcoidosis because it can detect active inflammatory granulomatous disease. However, active sarcoidosis lesions are observed to be hypermetabolic on FDG-PET/CT much like malignancies, which may lead to misinterpretation on imaging. In this case report, we present a rare case of sarcoidosis with multisystem involvement including lung, lymph nodes, bone, pleura, and soft tissue that mimicked lymphoma on FDG-PET/CT and responded to corticosteroid treatment.